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The Chilling Effect: How Do Researchers React to Controversy?
Drawing on interview and survey data from NIH-funded researchers, Joanna Kempner finds that political controversies can shape what scientists choose to study or not to study.
Image Credit: annieo76.
Revisiting the Design of Phase III Clinical Trials of Antimalarial Drugs for Uncomplicated Plasmodium falciparum Malaria
Steffen Borrmann and colleagues discuss appropriate endpoints and their measurement during phase III trials of new antimalarial drugs. This study is discussed in a related Perspective by Colin Sutherland.
Image credit: Dr. Johannes Friesen
Perspectives in PLoS Medicine
Perspective articles are commissioned from an expert and discuss the clinical practice or public health implications of a research article published in a PLoS journal. Some recent examples of Perspectives published in PLoS Medicine follow. You can find the link for the related research article in the right hand navigation bar of each piece.
In the News
In a Policy Forum published recently in PLoS Medicine, Adriane Fugh-Berman and Douglas Melnick described techniques by which pharmaceutical companies covertly promote off-label drug use even where such promotion is illegal. This paper has been widely covered by the media, a selection of which follows:
SciVee Pubcasts of PLoS Medicine Papers
SciVee is a website that enables researchers to combine a video or an audio presentation with their published scientific paper to create a pubcast. You can listen to video summaries of recent PLoS Medicine articles and read the full texts of these papers via the following links:
- The Effect of Universal Influenza Immunization on Mortality and Health Care Use
- Effect of the California Tobacco Control Program on Personal Health Care Expenditures
- Adapting the DOTS Framework for Tuberculosis Control to the Management of Non-Communicable Diseases in Sub-Saharan Africa
- Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis
From the Other PLoS Journals
October 2008 Issue
PLoS Medicine is a peer-reviewed, international, open-access journal publishing important original research and analysis relevant to human health.
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From the Web
The previous work of Joanna Kempner on self-censorship by scientists, whose current research is published in this week's PLoS Medicine, is described in a 2005 National Geographic article.
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